Synthesis of trifluoromethyl γ-aminophosphonates by nucleophilic aziridine ring opening.
نویسندگان
چکیده
Phosphonated derivatives of trifluoromethyl aziridine were obtained with good yield from aziridine-2-carbaldehyde by two distinct methods, which resulted in different diastereoselectivities. Using thiols as nucleophiles ring opening reactions of trifluoromethylated derivatives of aziridine-2-phosphonates proceeded regio- and diastereoselectively, giving rise to γ-amino-γ-trifluoromethyl phosphonates.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 39 شماره
صفحات -
تاریخ انتشار 2015